Validating a Coarse-Grained Potential Energy Function through Protein Loop Modelling

Coarse-grained (CG) methods for sampling protein conformational space have the potential to increase computational efficiency by reducing the degrees of freedom. The gain in computational efficiency of CG methods often comes at the expense of non-protein like local conformational features. This coul...

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Detalles Bibliográficos
Autores principales: MacDonald, James T., Kelley, Lawrence A., Freemont, Paul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688807/
https://www.ncbi.nlm.nih.gov/pubmed/23824634
http://dx.doi.org/10.1371/journal.pone.0065770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688807/
https://www.ncbi.nlm.nih.gov/pubmed/23824634
http://dx.doi.org/10.1371/journal.pone.0065770

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