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Differential Regulation of MAPK Phosphorylation in the Dorsal Hippocampus in Response to Prolonged Morphine Withdrawal-Induced Depressive-Like Symptoms in Mice

Depression is one of the most frequent neuropsychiatric comorbidities associated with opiate addiction. Mitogen activated protein kinase (MAPK) and MAPK phosphatase (MKP) are involved in drug addiction and depression. However, the potential role of MAPK and MKP in depression caused by morphine withd...

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Detalles Bibliográficos
Autores principales: Jia, Wei, Liu, Rui, Shi, Jianguo, Wu, Bin, Dang, Wei, Du, Ying, Zhou, Qiong, Wang, Jianhua, Zhang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688859/
https://www.ncbi.nlm.nih.gov/pubmed/23823128
http://dx.doi.org/10.1371/journal.pone.0066111