Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe

BACKGROUND: Controlled human malaria infection (CHMI) studies have become a routine tool to evaluate efficacy of candidate anti-malarial drugs and vaccines. To date, CHMI trials have mostly been conducted using the bite of infected mosquitoes, restricting the number of trial sites that can perform C...

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Detalles Bibliográficos
Autores principales: Sheehy, Susanne H., Spencer, Alexandra J., Douglas, Alexander D., Sim, B. Kim Lee, Longley, Rhea J., Edwards, Nick J., Poulton, Ian D., Kimani, Domtila, Williams, Andrew R., Anagnostou, Nicholas A., Roberts, Rachel, Kerridge, Simon, Voysey, Merryn, James, Eric R., Billingsley, Peter F., Gunasekera, Anusha, Lawrie, Alison M., Hoffman, Stephen L., Hill, Adrian V. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688861/
https://www.ncbi.nlm.nih.gov/pubmed/23823332
http://dx.doi.org/10.1371/journal.pone.0065960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688861/
https://www.ncbi.nlm.nih.gov/pubmed/23823332
http://dx.doi.org/10.1371/journal.pone.0065960

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