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The Expression of the fim Operon Is Crucial for the Survival of Streptococcus parasanguinis FW213 within Macrophages but Not Acid Tolerance

The acquisition of transition metal ions is essential for the viability and in some cases the expression of virulence genes in bacteria. The fimCBA operon of Streptococcus parasanguinis FW213 encodes a Mn(2+)/Fe(2+)-specific ATP-binding cassette transporter. FimA, a lipoprotein in the system, is ess...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Ywan M., Shieh, Hui-Ru, Chang, Ya-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688865/
https://www.ncbi.nlm.nih.gov/pubmed/23823757
http://dx.doi.org/10.1371/journal.pone.0066163