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Toxoplasma gondii Proliferation Require Down-Regulation of Host Nox4 Expression via Activation of PI3 Kinase/Akt Signaling Pathway

Toxoplasma gondii results in ocular toxoplasmosis characterized by chorioretinitis with inflammation and necrosis of the neuroretina, pigment epithelium, and choroid. After invasion, T. gondii replicates in host cells before cell lysis, which releases the parasites to invade neighboring cells to rep...

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Detalles Bibliográficos
Autores principales: Zhou, Wei, Quan, Juan-Hua, Lee, Young-Ha, Shin, Dae-Whan, Cha, Guang-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688893/
https://www.ncbi.nlm.nih.gov/pubmed/23824914
http://dx.doi.org/10.1371/journal.pone.0066306