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Toxoplasma gondii Proliferation Require Down-Regulation of Host Nox4 Expression via Activation of PI3 Kinase/Akt Signaling Pathway
Toxoplasma gondii results in ocular toxoplasmosis characterized by chorioretinitis with inflammation and necrosis of the neuroretina, pigment epithelium, and choroid. After invasion, T. gondii replicates in host cells before cell lysis, which releases the parasites to invade neighboring cells to rep...
Autores principales: | Zhou, Wei, Quan, Juan-Hua, Lee, Young-Ha, Shin, Dae-Whan, Cha, Guang-Ho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688893/ https://www.ncbi.nlm.nih.gov/pubmed/23824914 http://dx.doi.org/10.1371/journal.pone.0066306 |
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