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Prolonged Ketamine Effects in Sp4 Hypomorphic Mice: Mimicking Phenotypes of Schizophrenia

It has been well established that schizophrenia patients display impaired NMDA receptor (NMDAR) functions as well as exacerbation of symptoms in response to NMDAR antagonists. Abnormal NMDAR signaling presumably contributes to cognitive deficits which substantially contribute to functional disabilit...

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Detalles Bibliográficos
Autores principales: Ji, Baohu, Wang, Xin, Pinto-Duarte, Antonio, Kim, Minjung, Caldwell, Sorana, Young, Jared W., Behrens, Margarita M., Sejnowski, Terrence J., Geyer, Mark A., Zhou, Xianjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688895/
https://www.ncbi.nlm.nih.gov/pubmed/23823008
http://dx.doi.org/10.1371/journal.pone.0066327