A Novel Anticancer Agent, 8-Methoxypyrimido[4′,5′:4,5]thieno(2,3-b) Quinoline-4(3H)-One Induces Neuro 2a Neuroblastoma Cell Death through p53-Dependent, Caspase-Dependent and -Independent Apoptotic Pathways

Neuroblastoma is the most common cancer in infants and fourth most common cancer in children. Despite recent advances in cancer treatments, the prognosis of stage-IV neuroblastoma patients continues to be dismal which warrant new pharmacotherapy. A novel tetracyclic condensed quinoline compound, 8-m...

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Detalles Bibliográficos
Autores principales: Sahu, Upasana, Sidhar, Himakshi, Ghate, Pankaj S., Advirao, Gopal M., Raghavan, Sathees C., Giri, Ranjit K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688904/
https://www.ncbi.nlm.nih.gov/pubmed/23824039
http://dx.doi.org/10.1371/journal.pone.0066430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688904/
https://www.ncbi.nlm.nih.gov/pubmed/23824039
http://dx.doi.org/10.1371/journal.pone.0066430

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