Cellular FRET-Biosensors to Detect Membrane Targeting Inhibitors of N-Myristoylated Proteins

Hundreds of eukaryotic signaling proteins require myristoylation to functionally associate with intracellular membranes. N-myristoyl transferases (NMT) responsible for this modification are established drug targets in cancer and infectious diseases. Here we describe NANOMS (NANOclustering and Myrist...

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Detalles Bibliográficos
Autores principales: Najumudeen, Arafath Kaja, Köhnke, Monika, Šolman, Maja, Alexandrov, Kirill, Abankwa, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688908/
https://www.ncbi.nlm.nih.gov/pubmed/23824448
http://dx.doi.org/10.1371/journal.pone.0066425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688908/
https://www.ncbi.nlm.nih.gov/pubmed/23824448
http://dx.doi.org/10.1371/journal.pone.0066425

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