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Src Dependent Pancreatic Acinar Injury Can Be Initiated Independent of an Increase in Cytosolic Calcium

Several deleterious intra-acinar phenomena are simultaneously triggered on initiating acute pancreatitis. These culminate in acinar injury or inflammatory mediator generation in vitro and parenchymal damage in vivo. Supraphysiologic caerulein is one such initiator which simultaneously activates nume...

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Detalles Bibliográficos
Autores principales: Mishra, Vivek, Cline, Rachel, Noel, Pawan, Karlsson, Jenny, Baty, Catherine J., Orlichenko, Lidiya, Patel, Krutika, Trivedi, Ram Narayan, Husain, Sohail Z., Acharya, Chathur, Durgampudi, Chandra, Stolz, Donna B., Navina, Sarah, Singh, Vijay P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688910/
https://www.ncbi.nlm.nih.gov/pubmed/23824669
http://dx.doi.org/10.1371/journal.pone.0066471