Ribose Supplementation Alone or with Elevated Creatine Does Not Preserve High Energy Nucleotides or Cardiac Function in the Failing Mouse Heart

BACKGROUND: Reduced levels of creatine and total adenine nucleotides (sum of ATP, ADP and AMP) are hallmarks of chronic heart failure and restoring these pools is predicted to be beneficial by maintaining the diseased heart in a more favourable energy state. Ribose supplementation is thought to supp...

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Detalles Bibliográficos
Autores principales: Faller, Kiterie M. E., Medway, Debra J., Aksentijevic, Dunja, Sebag-Montefiore, Liam, Schneider, Jürgen E., Lygate, Craig A., Neubauer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688916/
https://www.ncbi.nlm.nih.gov/pubmed/23823183
http://dx.doi.org/10.1371/journal.pone.0066461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688916/
https://www.ncbi.nlm.nih.gov/pubmed/23823183
http://dx.doi.org/10.1371/journal.pone.0066461

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