Diminished Memory T-Cell Expansion Due to Delayed Kinetics of Antigen Expression by Lentivectors

Memory CD8(+) T lymphocytes play a central role in protective immunity. In attempt to increase the frequencies of memory CD8(+) T cells, repeated immunizations with viral vectors are regularly explored. Lentivectors have emerged as a powerful vaccine modality with relatively low pre-existing and ant...

Descripción completa

Detalles Bibliográficos
Autores principales: Furmanov, Karina, Elnekave, Mazal, Sa'eed, Abdallah, Segev, Hadas, Eli-Berchoer, Luba, Kotton, Darrell N., Bachrach, Gilad, Hovav, Avi-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688922/
https://www.ncbi.nlm.nih.gov/pubmed/23824049
http://dx.doi.org/10.1371/journal.pone.0066488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688922/
https://www.ncbi.nlm.nih.gov/pubmed/23824049
http://dx.doi.org/10.1371/journal.pone.0066488

Ejemplares similares