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Diminished Memory T-Cell Expansion Due to Delayed Kinetics of Antigen Expression by Lentivectors
Memory CD8(+) T lymphocytes play a central role in protective immunity. In attempt to increase the frequencies of memory CD8(+) T cells, repeated immunizations with viral vectors are regularly explored. Lentivectors have emerged as a powerful vaccine modality with relatively low pre-existing and ant...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688922/ https://www.ncbi.nlm.nih.gov/pubmed/23824049 http://dx.doi.org/10.1371/journal.pone.0066488 |