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Genome-Wide Gene Expression Profiling Revealed a Critical Role for GATA3 in the Maintenance of the Th2 Cell Identity

Functionally polarized CD4+ T helper (Th) cells such as Th1, Th2 and Th17 cells are central to the regulation of acquired immunity. However, the molecular mechanisms governing the maintenance of the polarized functions of Th cells remain unclear. GATA3, a master regulator of Th2 cell differentiation...

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Detalles Bibliográficos
Autores principales: Sasaki, Tetsuya, Onodera, Atsushi, Hosokawa, Hiroyuki, Watanabe, Yukiko, Horiuchi, Shu, Yamashita, Junji, Tanaka, Hitoshi, Ogawa, Yasumasa, Suzuki, Yutaka, Nakayama, Toshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688927/
https://www.ncbi.nlm.nih.gov/pubmed/23824597
http://dx.doi.org/10.1371/journal.pone.0066468