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Development of Adenoviral Delivery Systems to Target Hepatic Stellate Cells In Vivo

Hepatic stellate cells (HSCs) are known as initiator cells that induce liver fibrosis upon intoxication or other noxes. Deactivation of this ongoing remodeling process of liver parenchyma into fibrotic tissue induced by HSCs is an interesting goal to be achieved by targeted genetic modification of H...

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Detalles Bibliográficos
Autores principales: Reetz, Julia, Genz, Berit, Meier, Claudia, Kowtharapu, Bhavani S., Timm, Franziska, Vollmar, Brigitte, Herchenröder, Ottmar, Abshagen, Kerstin, Pützer, Brigitte M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688967/
https://www.ncbi.nlm.nih.gov/pubmed/23825626
http://dx.doi.org/10.1371/journal.pone.0067091