Detailed Analysis of Focal Chromosome Arm 1q and 6p Amplifications in Urothelial Carcinoma Reveals Complex Genomic Events on 1q, and SOX4 as a Possible Auxiliary Target on 6p

BACKGROUND: Urothelial carcinoma shows frequent amplifications at 6p22 and 1q21–24. The main target gene at 6p22 is believed to be E2F3, frequently co-amplified with CDKAL1 and SOX4. There are however reports on 6p22 amplifications that do not include E2F3. Previous analyses have identified frequent...

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Detalles Bibliográficos
Autores principales: Eriksson, Pontus, Aine, Mattias, Sjödahl, Gottfrid, Staaf, Johan, Lindgren, David, Höglund, Mattias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688975/
https://www.ncbi.nlm.nih.gov/pubmed/23825644
http://dx.doi.org/10.1371/journal.pone.0067222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688975/
https://www.ncbi.nlm.nih.gov/pubmed/23825644
http://dx.doi.org/10.1371/journal.pone.0067222

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