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Multimodal Treatment Eliminates Cancer Stem Cells and Leads to Long-Term Survival in Primary Human Pancreatic Cancer Tissue Xenografts

PURPOSE: In spite of intense research efforts, pancreatic ductal adenocarcinoma remains one of the most deadly malignancies in the world. We and others have previously identified a subpopulation of pancreatic cancer stem cells within the tumor as a critical therapeutic target and additionally shown...

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Detalles Bibliográficos
Autores principales: Hermann, Patrick C., Trabulo, Sara M., Sainz, Bruno, Balic, Anamaria, Garcia, Elena, Hahn, Stephan A., Vandana, Mallaredy, Sahoo, Sanjeeb K., Tunici, Patrizia, Bakker, Annette, Hidalgo, Manuel, Heeschen, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688976/
https://www.ncbi.nlm.nih.gov/pubmed/23825539
http://dx.doi.org/10.1371/journal.pone.0066371