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Multimodal Treatment Eliminates Cancer Stem Cells and Leads to Long-Term Survival in Primary Human Pancreatic Cancer Tissue Xenografts
PURPOSE: In spite of intense research efforts, pancreatic ductal adenocarcinoma remains one of the most deadly malignancies in the world. We and others have previously identified a subpopulation of pancreatic cancer stem cells within the tumor as a critical therapeutic target and additionally shown...
Autores principales: | Hermann, Patrick C., Trabulo, Sara M., Sainz, Bruno, Balic, Anamaria, Garcia, Elena, Hahn, Stephan A., Vandana, Mallaredy, Sahoo, Sanjeeb K., Tunici, Patrizia, Bakker, Annette, Hidalgo, Manuel, Heeschen, Christopher |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688976/ https://www.ncbi.nlm.nih.gov/pubmed/23825539 http://dx.doi.org/10.1371/journal.pone.0066371 |
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