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Optimized Infectivity of the Cell-Free Single-Cycle Human Immunodeficiency Viruses Type 1 (HIV-1) and Its Restriction by Host Cells

The infectivity of retroviruses such as HIV-1 in plasma or cultured media is less than 0.1% in general, the mechanisms of which are not yet fully understood. One possible explanation among others is the potential presence of large numbers of defective virions in a virus pool, which limits the appare...

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Detalles Bibliográficos
Autores principales: Kim, Jin H., Song, Hanna, Austin, Jamie L., Cheng, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688982/
https://www.ncbi.nlm.nih.gov/pubmed/23825637
http://dx.doi.org/10.1371/journal.pone.0067170