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Neonatal Diabetes Caused by Activating Mutations in the Sulphonylurea Receptor
Adenosine triphosphate (ATP)-sensitive potassium (K(ATP)) channels in pancreatic β-cells play a crucial role in insulin secretion and glucose homeostasis. These channels are composed of two subunits: a pore-forming subunit (Kir6.2) and a regulatory subunit (sulphonylurea receptor-1). Recent studies...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Korean Diabetes Association
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689011/ https://www.ncbi.nlm.nih.gov/pubmed/23807917 http://dx.doi.org/10.4093/dmj.2013.37.3.157 |