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Neonatal Diabetes Caused by Activating Mutations in the Sulphonylurea Receptor

Adenosine triphosphate (ATP)-sensitive potassium (K(ATP)) channels in pancreatic β-cells play a crucial role in insulin secretion and glucose homeostasis. These channels are composed of two subunits: a pore-forming subunit (Kir6.2) and a regulatory subunit (sulphonylurea receptor-1). Recent studies...

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Detalles Bibliográficos
Autor principal: Proks, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689011/
https://www.ncbi.nlm.nih.gov/pubmed/23807917
http://dx.doi.org/10.4093/dmj.2013.37.3.157