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Dendritic Cells in the Periphery Control Antigen-Specific Natural and Induced Regulatory T Cells

Dendritic cells (DCs) are specialized antigen-presenting cells that regulate both immunity and tolerance. DCs in the periphery play a key role in expanding naturally occurring Foxp3(+) CD25(+) CD4(+) regulatory T cells (Natural T-regs) and inducing Foxp3 expression (Induced T-regs) in Foxp3(−) CD4(+...

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Detalles Bibliográficos
Autores principales: Yamazaki, Sayuri, Morita, Akimichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689032/
https://www.ncbi.nlm.nih.gov/pubmed/23801989
http://dx.doi.org/10.3389/fimmu.2013.00151