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Gene delivery in a mouse xenograft of a retargeted retrovirus to a solid 143B osteosarcoma

BACKGROUND: Osteosarcomas are the most common primary bone malignancies found in children and adolescents. An optimized system was developed for efficient retroviral gene delivery into solid 143B osteosarcoma tumors in mice using a retargeted Env. In these studies, the viral Env CP was isolated from...

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Detalles Bibliográficos
Autores principales: Zhang, Xia, Sarangi, Anindita, Wu, Dai-Tze, Kanduri, Jaya, Roth, Monica J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689073/
https://www.ncbi.nlm.nih.gov/pubmed/23767896
http://dx.doi.org/10.1186/1743-422X-10-194