High correlation between in vivo [(123)I]β-CIT SPECT/CT imaging and post-mortem immunohistochemical findings in the evaluation of lesions induced by 6-OHDA in rats

BACKGROUND: 6-Hydroxydopamine (6-OHDA) is widely used in pre-clinical animal studies to induce degeneration of midbrain dopamine neurons to create animal models of Parkinson's disease. The aim of our study was to evaluate the potential of combined single-photon emission computed tomography/comp...

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Detalles Bibliográficos
Autores principales: Bäck, Susanne, Raki, Mari, Tuominen, Raimo K, Raasmaja, Atso, Bergström, Kim, Männistö, Pekka T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689076/
https://www.ncbi.nlm.nih.gov/pubmed/23758882
http://dx.doi.org/10.1186/2191-219X-3-46

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689076/
https://www.ncbi.nlm.nih.gov/pubmed/23758882
http://dx.doi.org/10.1186/2191-219X-3-46

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