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Lifetime congenital isolated GH deficiency does not protect from the development of diabetes

OBJECTIVES: Adult subjects with untreated, lifetime, isolated GH deficiency (IGHD) due to a homozygous GHRH receptor gene mutation (MUT/MUT) residing in Itabaianinha, Brazil, present with lower BMI, higher prevalence of impaired glucose tolerance (IGT), increased insulin sensitivity (IS), and reduce...

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Detalles Bibliográficos
Autores principales: Vicente, Taísa A R, Rocha, Ívina E S, Salvatori, Roberto, Oliveira, Carla R P, Pereira, Rossana M C, Souza, Anita H O, Campos, Viviane C, Santos, Elenilde G, Diniz, Rachel D C Araújo, Valença, Eugênia H O, Epitácio-Pereira, Carlos C, Oliveira, Mario C P, Mari, Andrea, Aguiar-Oliveira, Manuel H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioScientifica 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689269/
https://www.ncbi.nlm.nih.gov/pubmed/23795286
http://dx.doi.org/10.1530/EC-13-0014