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Down-regulation of the cancer/testis antigen 45 (CT45) is associated with altered tumor cell morphology, adhesion and migration

BACKGROUND: Due to their restricted expression in male germ cells and certain tumors, cancer/testis (CT) antigens are regarded as promising targets for tumor therapy. CT45 is a recently identified nuclear CT antigen that was associated with a severe disease score in Hodgkin’s lymphoma and poor progn...

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Detalles Bibliográficos
Autores principales: Koop, Anja, Sellami, Nadia, Adam-Klages, Sabine, Lettau, Marcus, Kabelitz, Dieter, Janssen, Ottmar, Heidebrecht, Hans-Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689639/
https://www.ncbi.nlm.nih.gov/pubmed/23758873
http://dx.doi.org/10.1186/1478-811X-11-41