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Differential Changes in Expression of Stress- and Metabolic-Related Neuropeptides in the Rat Hypothalamus during Morphine Dependence and Withdrawal

Chronic morphine treatment and naloxone precipitated morphine withdrawal activates stress-related brain circuit and results in significant changes in food intake, body weight gain and energy metabolism. The present study aimed to reveal hypothalamic mechanisms underlying these effects. Adult male ra...

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Detalles Bibliográficos
Autores principales: Pintér-Kübler, Bernadett, Ferenczi, Szilamér, Núnez, Cristina, Zelei, Edina, Polyák, Ágnes, Milanés, M. Victoria, Kovács, Krisztina J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689674/
https://www.ncbi.nlm.nih.gov/pubmed/23805290
http://dx.doi.org/10.1371/journal.pone.0067027