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Identification of Host Kinase Genes Required for Influenza Virus Replication and the Regulatory Role of MicroRNAs

Human protein kinases (HPKs) have profound effects on cellular responses. To better understand the role of HPKs and the signaling networks that influence influenza virus replication, a small interfering RNA (siRNA) screen of 720 HPKs was performed. From the screen, 17 HPKs (NPR2, MAP3K1, DYRK3, EPHA...

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Detalles Bibliográficos
Autores principales: Bakre, Abhijeet, Andersen, Lauren E., Meliopoulos, Victoria, Coleman, Keegan, Yan, Xiuzhen, Brooks, Paula, Crabtree, Jackelyn, Tompkins, S. Mark, Tripp, Ralph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689682/
https://www.ncbi.nlm.nih.gov/pubmed/23805279
http://dx.doi.org/10.1371/journal.pone.0066796