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Functional Integration of the Conserved Domains of Shoc2 Scaffold

Shoc2 is a positive regulator of signaling to extracellular signal-regulated protein kinases 1 and 2 (ERK1/2). Shoc2 is also proposed to interact with RAS and Raf-1 in order to accelerate ERK1/2 activity. To understand the mechanisms by which Shoc2 regulates ERK1/2 activation by the epidermal growth...

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Detalles Bibliográficos
Autores principales: Jeoung, Myoungkun, Abdelmoti, Lina, Jang, Eun Ryoung, Vander Kooi, Craig W., Galperin, Emilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689688/
https://www.ncbi.nlm.nih.gov/pubmed/23805200
http://dx.doi.org/10.1371/journal.pone.0066067