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Regulator of G-Protein Signalling-14 (RGS14) Regulates the Activation of αMβ2 Integrin during Phagocytosis

Integrin-mediated phagocytosis, an important physiological activity undertaken by professional phagocytes, requires bidirectional signalling to/from αMβ2 integrin and involves Rap1 and Rho GTPases. The action of Rap1 and the cytoskeletal protein talin in activating αMβ2 integrins, in a RIAM-independ...

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Detalles Bibliográficos
Autores principales: Lim, Jenson, Thompson, Jo, May, Robin C., Hotchin, Neil A., Caron, Emmanuelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689692/
https://www.ncbi.nlm.nih.gov/pubmed/23805333
http://dx.doi.org/10.1371/journal.pone.0069163