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FoxO3a Serves as a Biomarker of Oxidative Stress in Human Lens Epithelial Cells under Conditions of Hyperglycemia

BACKGROUND: Forkhead box ‘O’ transcription factors (FoxOs) are implicated in the pathogenesis of type2 diabetes and other metabolic diseases. Abnormal activity of FoxOs was reported in the glucose and insulin metabolism. Expression of FoxO proteins was reported in ocular tissues; however their funct...

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Detalles Bibliográficos
Autores principales: Raju, Ilangovan, Kannan, Krishnaswamy, Abraham, Edathara C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689697/
https://www.ncbi.nlm.nih.gov/pubmed/23805295
http://dx.doi.org/10.1371/journal.pone.0067126