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Effects of Chronic D-Serine Elevation on Animal Models of Depression and Anxiety-Related Behavior

NMDA receptors are activated after binding of the agonist glutamate to the NR2 subunit along with a co-agonist, either L-glycine or D-serine, to the NR1 subunit. There is substantial evidence to suggest that D-serine is the most relevant co-agonist in forebrain regions and that alterations in D-seri...

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Detalles Bibliográficos
Autores principales: Otte, David-Marian, Barcena de Arellano, Maria Luisa, Bilkei-Gorzo, Andras, Albayram, Önder, Imbeault, Sophie, Jeung, Haang, Alferink, Judith, Zimmer, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689701/
https://www.ncbi.nlm.nih.gov/pubmed/23805296
http://dx.doi.org/10.1371/journal.pone.0067131