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The Expression of SIRT1 and DBC1 in Laryngeal and Hypopharyngeal Carcinomas

RATIONALE AND OBJECTIVE: Sirtuin 1 (SIRT1) plays an important role in tumorigenesis and is increased in many human tumors. DBC1 is a negative regulator of SIRT1 via promotion of p53-mediated apoptosis. It is necessary to investigate the expression of SIRT1 and DBC1 in laryngeal and hypopharyngeal sq...

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Detalles Bibliográficos
Autores principales: Yu, Xue-Min, Liu, Ying, Jin, Tong, Liu, Jun, Wang, Juan, Ma, Chao, Pan, Xin-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689713/
https://www.ncbi.nlm.nih.gov/pubmed/23805287
http://dx.doi.org/10.1371/journal.pone.0066975