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Intestine-Specific Mttp Deletion Increases the Severity of Experimental Colitis and Leads to Greater Tumor Burden in a Model of Colitis Associated Cancer

BACKGROUND: Gut derived lipid factors have been implicated in systemic injury and inflammation but the precise pathways involved are unknown. In addition, dietary fat intake and obesity are independent risk factors for the development of colorectal cancer. Here we studied the severity of experimenta...

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Detalles Bibliográficos
Autores principales: Xie, Yan, Matsumoto, Hitoshi, Nalbantoglu, ILKe, Kerr, Thomas A., Luo, Jianyang, Rubin, Deborah C., Kennedy, Susan, Davidson, Nicholas O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689718/
https://www.ncbi.nlm.nih.gov/pubmed/23805328
http://dx.doi.org/10.1371/journal.pone.0067819