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Two Distinct Categories of Focal Deletions in Cancer Genomes

One of the key questions about genomic alterations in cancer is whether they are functional in the sense of contributing to the selective advantage of tumor cells. The frequency with which an alteration occurs might reflect its ability to increase cancer cell growth, or alternatively, enhanced insta...

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Detalles Bibliográficos
Autores principales: Rajaram, Megha, Zhang, Jianping, Wang, Tim, Li, Jinyu, Kuscu, Cem, Qi, Huan, Kato, Mamoru, Grubor, Vladimir, Weil, Robert J., Helland, Aslaug, Borrenson-Dale, Anne-Lise, Cho, Kathleen R., Levine, Douglas A., Houghton, Alan N., Wolchok, Jedd D., Myeroff, Lois, Markowitz, Sanford D., Lowe, Scott W., Zhang, Michael, Krasnitz, Alex, Lucito, Robert, Mu, David, Powers, R. Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689739/
https://www.ncbi.nlm.nih.gov/pubmed/23805207
http://dx.doi.org/10.1371/journal.pone.0066264