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Two Distinct Categories of Focal Deletions in Cancer Genomes
One of the key questions about genomic alterations in cancer is whether they are functional in the sense of contributing to the selective advantage of tumor cells. The frequency with which an alteration occurs might reflect its ability to increase cancer cell growth, or alternatively, enhanced insta...
Autores principales: | Rajaram, Megha, Zhang, Jianping, Wang, Tim, Li, Jinyu, Kuscu, Cem, Qi, Huan, Kato, Mamoru, Grubor, Vladimir, Weil, Robert J., Helland, Aslaug, Borrenson-Dale, Anne-Lise, Cho, Kathleen R., Levine, Douglas A., Houghton, Alan N., Wolchok, Jedd D., Myeroff, Lois, Markowitz, Sanford D., Lowe, Scott W., Zhang, Michael, Krasnitz, Alex, Lucito, Robert, Mu, David, Powers, R. Scott |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689739/ https://www.ncbi.nlm.nih.gov/pubmed/23805207 http://dx.doi.org/10.1371/journal.pone.0066264 |
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