Oligomerization of Peptides LVEALYL and RGFFYT and Their Binding Affinity to Insulin

Recently it has been proposed a model for fibrils of human insulin in which the fibril growth proceeds via stacking LVEALYL (fragment 11–17 from chain B of insulin) into pairs of tightly interdigitated [Image: see text]-sheets. The experiments have also shown that LVEALYL has high propensity to self...

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Detalles Bibliográficos
Autores principales: Chiang, Hsin-Lin, Ngo, Son Tung, Chen, Chun-Jung, Hu, Chin-Kun, Li, Mai Suan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689759/
https://www.ncbi.nlm.nih.gov/pubmed/23805182
http://dx.doi.org/10.1371/journal.pone.0065358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689759/
https://www.ncbi.nlm.nih.gov/pubmed/23805182
http://dx.doi.org/10.1371/journal.pone.0065358

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