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Oligomerization of Peptides LVEALYL and RGFFYT and Their Binding Affinity to Insulin
Recently it has been proposed a model for fibrils of human insulin in which the fibril growth proceeds via stacking LVEALYL (fragment 11–17 from chain B of insulin) into pairs of tightly interdigitated [Image: see text]-sheets. The experiments have also shown that LVEALYL has high propensity to self...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689759/ https://www.ncbi.nlm.nih.gov/pubmed/23805182 http://dx.doi.org/10.1371/journal.pone.0065358 |