A Hypomorphic Mutation Reveals a Stringent Requirement for the ATM Checkpoint Protein in Telomere Protection During Early Cell Division in Drosophila

Using Drosophila as a model system, we identified a stringent requirement for the conserved function of Ataxia Telangiectasia Mutated (ATM) in telomere protection during early embryonic development. Animals homozygous for a hypomorphic mutation in atm develop normally with minimal telomere dysfuncti...

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Detalles Bibliográficos
Autores principales: Morciano, Patrizia, Zhang, Yi, Cenci, Giovanni, Rong, Yikang S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2013
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689801/
https://www.ncbi.nlm.nih.gov/pubmed/23604076
http://dx.doi.org/10.1534/g3.113.006312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689801/
https://www.ncbi.nlm.nih.gov/pubmed/23604076
http://dx.doi.org/10.1534/g3.113.006312

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