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A Hypomorphic Mutation Reveals a Stringent Requirement for the ATM Checkpoint Protein in Telomere Protection During Early Cell Division in Drosophila

Using Drosophila as a model system, we identified a stringent requirement for the conserved function of Ataxia Telangiectasia Mutated (ATM) in telomere protection during early embryonic development. Animals homozygous for a hypomorphic mutation in atm develop normally with minimal telomere dysfuncti...

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Detalles Bibliográficos
Autores principales:	Morciano, Patrizia, Zhang, Yi, Cenci, Giovanni, Rong, Yikang S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2013
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689801/ https://www.ncbi.nlm.nih.gov/pubmed/23604076 http://dx.doi.org/10.1534/g3.113.006312

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