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PUMA Cooperates with p21 to Regulate Mammary Epithelial Morphogenesis and Epithelial-To-Mesenchymal Transition

Lumen formation is essential for mammary morphogenesis and requires proliferative suppression and apoptotic clearance of the inner cells within developing acini. Previously, we showed that knockdown of p53 or p73 leads to aberrant mammary acinus formation accompanied with decreased expression of p53...

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Detalles Bibliográficos
Autores principales: Zhang, Yanhong, Yan, Wensheng, Jung, Yong Sam, Chen, Xinbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689819/
https://www.ncbi.nlm.nih.gov/pubmed/23805223
http://dx.doi.org/10.1371/journal.pone.0066464