Cationic and PEGylated Amphiphilic Cyclodextrins: Co-Formulation Opportunities for Neuronal Sirna Delivery

Optimising non-viral vectors for neuronal siRNA delivery presents a significant challenge. Here, we investigate a co-formulation, consisting of two amphiphilic cyclodextrins (CDs), one cationic and the other PEGylated, which were blended together for siRNA delivery to a neuronal cell culture model....

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Detalles Bibliográficos
Autores principales: O’Mahony, Aoife M., Ogier, Julien, Darcy, Raphael, Cryan, John F., O’Driscoll, Caitriona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689829/
https://www.ncbi.nlm.nih.gov/pubmed/23805220
http://dx.doi.org/10.1371/journal.pone.0066413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689829/
https://www.ncbi.nlm.nih.gov/pubmed/23805220
http://dx.doi.org/10.1371/journal.pone.0066413

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