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Computational Model of Gab1/2-Dependent VEGFR2 Pathway to Akt Activation
Vascular endothelial growth factor (VEGF) signal transduction is central to angiogenesis in development and in pathological conditions such as cancer, retinopathy and ischemic diseases. However, no detailed mass-action models of VEGF receptor signaling have been developed. We constructed and validat...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689841/ https://www.ncbi.nlm.nih.gov/pubmed/23805312 http://dx.doi.org/10.1371/journal.pone.0067438 |