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HIV-1 Antiretroviral Resistance: Scientific Principles and Clinical Applications
The efficacy of an antiretroviral (ARV) treatment regimen depends on the activity of the regimen’s individual ARV drugs and the number of HIV-1 mutations required for the development of resistance to each ARV — the genetic barrier to resistance. ARV resistance impairs the response to therapy in pati...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689909/ https://www.ncbi.nlm.nih.gov/pubmed/22686620 http://dx.doi.org/10.2165/11633630-000000000-00000 |