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HIV-1 Antiretroviral Resistance: Scientific Principles and Clinical Applications

The efficacy of an antiretroviral (ARV) treatment regimen depends on the activity of the regimen’s individual ARV drugs and the number of HIV-1 mutations required for the development of resistance to each ARV — the genetic barrier to resistance. ARV resistance impairs the response to therapy in pati...

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Detalles Bibliográficos
Autores principales: Tang, Michele W., Shafer, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689909/
https://www.ncbi.nlm.nih.gov/pubmed/22686620
http://dx.doi.org/10.2165/11633630-000000000-00000