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Targeting Underglycosylated MUC1 for the Selective Capture of Highly Metastatic Breast Cancer Cells Under Flow

The underglycosylated form of the MUC1 glycoprotein, uMUC1, has been identified as a ligand for both E-selectin and ICAM-1 and can play multiple potential roles during rolling and firm adhesion events in the metastatic cascade. Using flow cytometry and confocal microscopy, the T47D and ZR-75-1 cell...

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Detalles Bibliográficos
Autores principales: Geng, Yue, Takatani, Tait, Yeh, Kimberly, Hsu, Jong-Wei, King, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689911/
https://www.ncbi.nlm.nih.gov/pubmed/23805168
http://dx.doi.org/10.1007/s12195-013-0282-y