Pharmacokinetic Dose Proportionality Between Two Strengths (12.5 mg and 25 mg) of Doxylamine Hydrogen Succinate Film-Coated Tablets in Fasting State: A Single-Dose, Randomized, Two-Period Crossover Study in Healthy Volunteers

BACKGROUND: Doxylamine succinate, an ethanolamine-based antihistamine, is used in the short-term management of insomnia because of its sedative effects. No data on the dose proportionality of the pharmacokinetics of doxylamine are available, although this drug has been marketed in European countries...

Descripción completa

Detalles Bibliográficos
Autores principales: Videla, Sebastián, Cebrecos, Jesús, Lahjou, Mounia, Wagner, France, Guibord, Pascal, Xu, Zhengguo, Cabot, Anna, Encabo, Mercedes, Encina, Gregorio, Sicard, Eric, Sans, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing AG 2013
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689913/
https://www.ncbi.nlm.nih.gov/pubmed/23633146
http://dx.doi.org/10.1007/s40268-013-0015-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689913/
https://www.ncbi.nlm.nih.gov/pubmed/23633146
http://dx.doi.org/10.1007/s40268-013-0015-7

Ejemplares similares