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Robust cytoplasmic accumulation of phosphorylated TDP-43 in transgenic models of tauopathy

Frontotemporal lobar degeneration (FTLD) has been subdivided based on the main pathology found in the brains of affected individuals. When the primary pathology is aggregated, hyperphosphorylated tau, the pathological diagnosis is FTLD-tau. When the primary pathology is cytoplasmic and/or nuclear ag...

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Detalles Bibliográficos
Autores principales: Clippinger, Amy K., D’Alton, Simon, Lin, Wen-Lang, Gendron, Tania F., Howard, John, Borchelt, David R., Cannon, Ashley, Carlomagno, Yari, Chakrabarty, Paramita, Cook, Casey, Golde, Todd E., Levites, Yona, Ranum, Laura, Schultheis, Patrick J., Xu, Guilian, Petrucelli, Leonard, Sahara, Naruhiko, Dickson, Dennis W., Giasson, Benoit, Lewis, Jada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690181/
https://www.ncbi.nlm.nih.gov/pubmed/23666556
http://dx.doi.org/10.1007/s00401-013-1123-8