Cargando…

Cold-induced RNA-binding proteins regulate circadian gene expression by controlling alternative polyadenylation

The body temperature is considered a universal cue by which the master clock synchronizes the peripheral clocks in mammals, but the mechanism is not fully understood. Here we identified two cold-induced RNA-binding proteins (RBPs), Cirbp and Rbm3, as important regulators for the temperature entraine...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Yuting, Hu, Wenchao, Murakawa, Yasuhiro, Yin, Jingwen, Wang, Gang, Landthaler, Markus, Yan, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690385/
https://www.ncbi.nlm.nih.gov/pubmed/23792593
http://dx.doi.org/10.1038/srep02054