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V-Shaped Dinuclear Pt(II) Complexes: Selective Interaction with Human Telomeric G-quadruplex and Significant Inhibition towards Telomerase
A quaternized trigeminal ligand, 4-[4,6-di(4-pyridyl)-1,3,5-(2-triazinyl)]-1-methylpyridine-1-ium hexafluorophosphate (dptmp·PF(6)), and two derivative V-shaped dinuclear Pt(II) complexes, {[Pt(dien)](2)(dptmp)}(PF(6))(5) (1) and {[Pt(dpa)](2)(dptmp)}(PF(6))(5) (2), were synthesized, characterized a...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690394/ https://www.ncbi.nlm.nih.gov/pubmed/23792883 http://dx.doi.org/10.1038/srep02060 |