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V-Shaped Dinuclear Pt(II) Complexes: Selective Interaction with Human Telomeric G-quadruplex and Significant Inhibition towards Telomerase

A quaternized trigeminal ligand, 4-[4,6-di(4-pyridyl)-1,3,5-(2-triazinyl)]-1-methylpyridine-1-ium hexafluorophosphate (dptmp·PF(6)), and two derivative V-shaped dinuclear Pt(II) complexes, {[Pt(dien)](2)(dptmp)}(PF(6))(5) (1) and {[Pt(dpa)](2)(dptmp)}(PF(6))(5) (2), were synthesized, characterized a...

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Detalles Bibliográficos
Autores principales:	Xu, Cui-Xia, Zheng, Yu-Xuan, Zheng, Xiao-Hui, Hu, Qian, Zhao, Yong, Ji, Liang-Nian, Mao, Zong-Wan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690394/ https://www.ncbi.nlm.nih.gov/pubmed/23792883 http://dx.doi.org/10.1038/srep02060

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